Clinical Research Trials : Complications of Chronic Liver Disease

Complications of Chronic Liver Disease

Hepatocellular Carcinoma

1. Target: A 5-year longitudinal, observational study of The Natural History and Management of Patients with Hepatocellular Carcinoma

  • Status: Open
  • PI: Dr. Patricia Jones
  • Coordinator: Tiffannia Grant
  • Contact: (305) 243-4649 / t.grant11@med.miami.edu

Hepatorenal Syndrome Type 1

1. Mallinckrodt: MNK19013058- Randomized, placebo study to confirm efficacy & safety of Terlipressin in subjects with Hepatorenal Syndrome Type 1

  • Status: Open
  • PI: Dr. Kalyan Bhamidimarri
  • Coordinator: Andrea Elibero
  • Contact: (305) 243-6968 / axe375@med.miami.edu

Thrombocytopenia

1. AVA-PST-320: An Open-Label Study to Evaluate the Efficacy and Safety of Avatrombopag for the Treatment of Subjects with Thrombocytopenia Scheduled for a Surgical Procedure

  • Status: Open
  • PI: Dr. Eric Martin
  • Coordinator: Andrea Elibero
  • Contact: (305) 243-6968 / axe375@med.miami.edu

2. AVA-CLD-401: An Observational Cohort Study of the Use of Avatrombopag in Patients with Thrombocytopenia Associated with Chronic Liver Disease Undergoing a Procedure

  • Status: Future Trial
  • PI: Dr. Cynthia Levy
  • Coordinator: Katherine Dae
  • Contact: (305) 243-1104 / kqd1@med.miami.edu

Hepatic Encephalopathy

1. RNHE2041: A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Multicenter Study to Assess the Efficacy and Safety of Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE)

  • Status: Open
  • PI: Dr. Eric Martin
  • Coordinator: Andrea Elibero
  • Contact: (305) 243-6968 / axe375@med.miami.edu